Anal margin cancer

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The anus is connected to the rectum by the anal canal. The anal canal has two ring-shaped muscles called sphincter muscles that keep the anus closed and prevent stool from leaking out. The anal verge is where the canal connects to the outside skin at the anus. This skin around the anal verge is called the perianal skin previously called the anal margin. The inner lining of the anal canal is the mucosa.

This paper consists of a review of the literature on carcinoma of the anal margin, as well as the authors' institutional experience with this uncommon malignancy. They recommend radiation alone or local excision for T1 lesions, radiation and elective nodal irradiation for T2 lesions, and chemoradiation, including irradiation of the primary tumor and inguinal and pelvic nodes, for T3 and T4 lesions. This paper consists of a review of the literature on carcinomaof the anal margin, as well as the authors' institutional experiencewith this uncommon malignancy. They recommend radiation aloneor local excision for T1 lesions, radiation and elective nodalirradiation for T2 lesions, and chemoradiation, including irradiationof the primary tumor and inguinal and pelvic nodes, for T3 andT4 lesions.

Management of Rare Adult Tumours pp Cite as. Cancers of the anal margin AM are cutaneous cancers peri-anal skin cancers occurring on the peri-anal area outside the anal verge. This funnel-shaped skin area is defined by a circle measuring 10 cm in diameter centred on the anal orifice.