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List of sex linked diseases

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Genetic Disorders and the Fetus pp Cite as. The human X chromosome constitutes one of the most intensively examined stretches of genetic material in a higher eukaryote. This is probably the result of certain technical features that facilitate the study and recognition of X-linked genes, the relative frequency of X-linked disorders as a group, and the quantitative importance of several specific conditions, such as Duchenne muscular dystrophy and hemophilia. It has been relatively easy to recognize X-encoded mutant genes by virtue of their typical pattern of inheritance, and several X-linked diseases have been known since antiquity.
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X-Linked Diseases and Disorders of the Sex Chromosomes

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X-Linked Diseases and Disorders of the Sex Chromosomes | SpringerLink

Sex-linked diseases are passed down through families through one of the X or Y chromosomes. X and Y are sex chromosomes. Dominant inheritance occurs when an abnormal gene from one parent causes disease, even though the matching gene from the other parent is normal. The abnormal gene dominates.
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Sex-linked Diseases: the Case of Duchenne Muscular Dystrophy (DMD)

Sex-linked dominant is a rare way that a trait or disorder can be passed down through families. One abnormal gene on the X chromosome can cause a sex-linked dominant disease. Inheritance of a specific disease, condition, or trait depends on the type of chromosome that is affected. It can be either an autosomal chromosome or a sex chromosome. It also depends on whether the trait is dominant or recessive.
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This page has been archived and is no longer updated. Knowledge about recessive X-linked gene-disease associations has led to the development and widespread use of prenatal diagnostic tests that can provide parents with information about whether their embryo or fetus might be carrying a disease mutation. Based on that information, the parents can either terminate the pregnancy or prepare for their future child, depending on their beliefs. You might expect that this kind of widespread testing has had the ultimate effect of decreasing the frequency of disease alleles in the population. In fact, the opposite is true, according to research by geneticist Ian Hastings of the Liverpool School of Tropical Medicine in England.
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